Development of gene expression signatures for the HDF and MDA-MB-231 cells that received TP4 (a cationic antimicrobial peptide) treatment
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ABSTRACT: Triple-negative breast cancer (TNBC) lacks therapeutic target and is difficult to treat. We report a cationic antimicrobial peptide (CAP), tilapia piscidin 4 (TP4), derived from Nile tilapia (Oreochromis niloticus), selectively toxic to TNBC. Here we aim to identify potential target in TNBC cell response to TP4 treatment by microarray study and to further address the role of TP4-resposive genes involved in TNBC cell death.
ORGANISM(S): Homo sapiens
PROVIDER: GSE74764 | GEO | 2016/12/31
SECONDARY ACCESSION(S): PRJNA301442
REPOSITORIES: GEO
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