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Circulating microRNAs: Association with lung function in asthma

ABSTRACT: Blood serum from 160 Childhood Asthma Management Program (CAMP) subjects were microRNA profiles with 13 subjects profiled twice. Each subject has diverse clinical phenotypes notably spirometry related phenotypes.

ORGANISM(S): Homo sapiens

PROVIDER: GSE74770 | GEO | 2016/06/09

SECONDARY ACCESSION(S): PRJNA301451

REPOSITORIES: GEO

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Circulating microRNAs: Association with lung function in asthma

Project description:Blood serum from 160 Childhood Asthma Management Program (CAMP) subjects were microRNA profiles with 13 subjects profiled twice. Each subject has diverse clinical phenotypes notably spirometry related phenotypes. Least squares linear regression was applied with subject phenotypes as the dependent variable, and microRNA Ct values (data matrix quantile normalized) as the independent variable to identify significant associations between subject phenotype and microRNA abundance.

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Genetic variants regulating ORMDL3 expression are determinants of susceptibility to childhood asthma

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