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Gene expression profile of sheep following dietary iodide supplementation

ABSTRACT: In the present study, we studied the effect of dietray iodide (IOD) supplementation on the transcriptome's profile of sheep. The main objective was to evaluate the effect of IOD-supplementation on the overall transcriptome of sheep, the altered pathways, and the biological processes related to it . A previously custom-designed oligo microarray platform (GPL20576) was used to profile the transcriptome of 10 ewes at two time points [T0 (before supplementation) and T40 (after 40-days supplementation period). The Isolated and purified total RNAs were individually hybridized to the custom (4x44k) DNA microarray. The comparison of unsupplemented and supplemented animals' transcriptome revealed a large set of differentially expressed genes. Functional analysis showed several pathways and biological processes that have been altered following IOD-supplementation to the diet.

ORGANISM(S): Ovis aries

PROVIDER: GSE74778 | GEO | 2019/12/26

REPOSITORIES: GEO

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Project description:Gene expression profile of sheep following dietary iodide supplementation

| PRJNA301464 | ENA

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