Transcriptomics

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A phase 1b study of the Akt-inhibitor MK-2206 in combination with weekly paclitaxel and trastuzumab in patients with advanced HER2-overexpressing solid tumor malignancies


ABSTRACT: 16 patients with HER2+ tumors were enrolled (12 breast, 3 gastric, 1 esophageal). 27 samples (12 primary + 15 metastatic) from the 16 unique patients were assayed on Agilent 60K expression microarrays, and association between expression and response data were evaluated to identify potential biomarker of MK2206 response

ORGANISM(S): Homo sapiens

PROVIDER: GSE75087 | GEO | 2016/07/31

SECONDARY ACCESSION(S): PRJNA302430

REPOSITORIES: GEO

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