Methylation profiling

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DNA methylation drift as a marker of lifespan in mammals [mouse]


ABSTRACT: We analyzed levels of 5-methyl cytosine at CCCGGG target sites by sequential restriction digest by SmaI and XmaI enzymes, ligating Illumina adaptors to the restriction fragments and reading methylation-specific signatures at the ends of restriction fragments by paired ends Illumina high throughput sequencing.

ORGANISM(S): Mus musculus

PROVIDER: GSE75495 | GEO | 2017/07/10

SECONDARY ACCESSION(S): PRJNA304429

REPOSITORIES: GEO

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