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Genome-wide characterization of Zac1 target genes reveals its role as a broad regulator of the imprinted gene network including extracellular matrix genes.

ABSTRACT: In order to determine the imprinted transcription factor Zac1 targets, we overexpressed Zac1 in a neuroblastoma cell line and measured both the regulated expressed genes by Differential Gene Expressed analysis and Zac1 binding sites throughout the mouse genome by ChIP-seq. We have shown that Zac1 regulates and binds closed to many genes belonging to the Imprinted Gene Network.

ORGANISM(S): Mus musculus

PROVIDER: GSE75943 | GEO | 2017/11/24

SECONDARY ACCESSION(S): PRJNA305758

REPOSITORIES: GEO

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Plagl1/Zac1 regulates extracellular matrix genes and the imprinted gene network

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Genome-wide characterization of Zac1 target genes reveals its role as a broad regulator of the imprinted gene network including extracellular matrix genes

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