Methylation profiling

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Methylation profile generated by reduced representation bisulfite sequencing (RRBS) of H2O2-treated and untreated HCT116 cells


ABSTRACT: DNA methylation is an important regulatory mechanism that contributes to transcriptional repression. To examine whether DNA methylation affects the transcriptional changes of DNA repair genes under H2O2-induced oxidative stress, we performed reduced representation bisulfite sequencing (RRBS) in H2O2-treated and untreated HCT116 cells.

ORGANISM(S): Homo sapiens

PROVIDER: GSE75963 | GEO | 2016/05/01

SECONDARY ACCESSION(S): PRJNA305865

REPOSITORIES: GEO

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