Transcriptomics

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Comprehensive genomic analysis identify novel subtypes and targets of triple-negative breast cancer (198 TNBC tumors)


ABSTRACT: Recent meta-analyses suggest triple-negative breast cancer (TNBC) is a heterogenous disease. In this study we sought to define these TNBC subtypes and identify subtype-specific markers and targets. We identified and confirmed four distinct, stable TNBC subtypes: (1) Luminal-AR (LAR); 2) Mesenchymal (MES); 3) Basal-Like Immune-Suppressed (BLIS), and 4) Basal-Like Immune-Activated (BLIA).

ORGANISM(S): Homo sapiens

PROVIDER: GSE76124 | GEO | 2015/12/18

SECONDARY ACCESSION(S): PRJNA306372

REPOSITORIES: GEO

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