Transcriptomics

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Genome wide comparison of the inducible transcriptomes of CAR, PXR and PPARα in primary human hepatocytes


ABSTRACT: To identify the CAR-, PXR- and PPARα-specific genome-wide expression changes, hepatocyte cultures from six individual donors were treated with the prototypical ligands for CAR (CITCO), PXR (rifampicin) and PPARα (WY14,643) as well as DMSO (vehicle control). Afterwards, the mRNA expression in these samples was determined utilizing Affymetrix® microarrays.

ORGANISM(S): Homo sapiens

PROVIDER: GSE76148 | GEO | 2016/03/24

SECONDARY ACCESSION(S): PRJNA306430

REPOSITORIES: GEO

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