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Expression data from additional molar germs at stages of early development in miniature pigs

ABSTRACT: We identified the spatiotemporal pattern of cascade initiation of additional molars in miniature pig,where second molar (M2) initiated from the posterior-free end of the dental lamina over the first molar (M1) at E60 when M1 progressed to the late bell stage. Similarly, third molar (M3) budded off from the posterior-free end of the dental lamina over M2, which reached bell stage at PN20. However, the molecular mechanisms of the regulatory network during sequential formation of additional molars remain poorly characterized in diphyodont mammals. We performed microarrays on miniature pigs at three molar developmental stages to examine their differential gene expression profiles and potential regulatory networks during additional molar morphogenesis.

ORGANISM(S): Sus scrofa

PROVIDER: GSE77006 | GEO | 2017/01/24

SECONDARY ACCESSION(S): PRJNA309243

REPOSITORIES: GEO

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