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Hyperglycaemia-induced over-expression of miR-301a promotes the proliferation of prostate cancer cells by repressing Smad4 and p21.

ABSTRACT: We found a novel molecular link between hyperglycaemia and the increased frequency of aggressive prostate cancer. High glucose was demonstrated to increase the expression of miR-301a which targeted Smad4 and p21, resulted in promoting the proliferation of prostate cancer cells.

ORGANISM(S): Rattus norvegicus

PROVIDER: GSE77092 | GEO | 2016/01/22

SECONDARY ACCESSION(S): PRJNA309419

REPOSITORIES: GEO

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