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Impact of mutations in rv2887, putative transcriptional repressor, on gene expression in Mycobacterium tuberculosis.

ABSTRACT: This study was aimed towards understanding the consequences of mutating rv2887, a putative transcriptional repressor, on gene expression in Mycobacterium tuberculosis. Since clones carrying mutations in this gene were found to be highly resistant to a potent mycobactericidal compound, 14, we also tested the impact of short-term exposure to this compound on gene expression in Mycobacterium tuberculosis.

ORGANISM(S): Mycobacterium tuberculosis

PROVIDER: GSE77556 | GEO | 2016/07/01

SECONDARY ACCESSION(S): PRJNA310781

REPOSITORIES: GEO

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