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Changes in the erythroblast miRNA profile in the bone marrow of a Plasmodium vivax-infected patient

ABSTRACT: Human studies of Plasmodium vivax in the bone marrow are scarce. Here, we present a detailed characterization of bone marrow aspirates taken from a P. vivax patient with high parasitaemia on admission and 42 days after treatment. Analysis of miRNAs related to erythropoiesis revealed a distinct series of differentially expressed miRNAs during infection compared to at convalescence. These results suggest that parasites in the bone marrow affect erythropoiesis.

ORGANISM(S): Homo sapiens

PROVIDER: GSE78516 | GEO | 2017/02/25

SECONDARY ACCESSION(S): PRJNA313197

REPOSITORIES: GEO

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