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Screening of differentially expressed genes after IMB5046 treatment

ABSTRACT: To investigate the effects of IMB5046 treatment on cells, we used the gene expression microarray to compare the difference between the IMB5046-treated cells and control cells. A431 cells were treated with 100 nM IMB5046 or 0.1% DMSO (vehicle) for 24 hr. A total of 441 genes were down-regulated and 383 genes were up-regulated by at least 2-fold between IMB5046-treated and control cells.The most obviuos changes in Gene Ontology biolocial process classification were related to cell death and immune response.

ORGANISM(S): Homo sapiens

PROVIDER: GSE78944 | GEO | 2016/03/08

SECONDARY ACCESSION(S): PRJNA314485

REPOSITORIES: GEO

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