Genomics

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Dermatophytes CGH based on a Trichophyton rubrum cDNA microarray


ABSTRACT: A cDNA microarray was constructed from the expressed sequence tags (ESTs) of different developmental stages, and comparative genome hybridization based on microarray procedures were carried out. Dermatophyte species are classified into three genera: Epidermophyton, Microsporum, and Trichophyton. To determine the relationship between these three groups comparative genome hybridization were used in our experiment. Trichophyton rubrum genmic DNA was reference DNA and labelled by Cy3 while the other dermatophytes genomic DNA were test DNA and labelled by CY5. Test and reference DNA were co-hybridized with the T. rubrum cDNA microarray and the numbers of genes shared between each species and T. rubrum were determined. Keywords: Comparative Genomic Hybridization

ORGANISM(S): Trichophyton verrucosum Arthroderma uncinatum Trichophyton longifusum Epidermophyton floccosum Microsporum ferrugineum Trichophyton rubrum Nannizzia gypsea Trichophyton benhamiae Nannizzia nana Trichophyton violaceum Paraphyton cookei Lophophyton gallinae Microsporum distortum Nannizzia racemosa Trichophyton schoenleinii Trichophyton soudanense Microsporum canis Arthroderma terrestre

PROVIDER: GSE7909 | GEO | 2010/05/04

SECONDARY ACCESSION(S): PRJNA100087

REPOSITORIES: GEO

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