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Expression data from murine GVH-SSc skin

ABSTRACT: Murine GVH-SSc dorsal scapular skin samples were analyzed to determine the effect of IFNAR-1 inhibition on gene expression at day 14 and day 28. Gene expression in GVH-SSc skin from mice treated with a neutralizing IFNAR-1 antibody was compared to that in GVH-SSc skin from mice treated with isotype IgG, with skin from syngeneic graft controls as reference.

ORGANISM(S): Mus musculus

PROVIDER: GSE79194 | GEO | 2016/03/16

SECONDARY ACCESSION(S): PRJNA315189

REPOSITORIES: GEO

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Expression data from murine GVH-SSc skin

Project description:Murine GVH-SSc dorsal scapular skin samples were analyzed to determine the effect of IFNAR-1 inhibition on gene expression at day 14 and day 28. Gene expression in GVH-SSc skin from mice treated with a neutralizing IFNAR-1 antibody was compared to that in GVH-SSc skin from mice treated with isotype IgG, with skin from syngeneic graft controls as reference. For each timepoint, the following samples were analyzed: syngeneic control (n=4); GVH-SSc isotype (n=4); GVH-SSc anti-IFNAR-1 (n=4)

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