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Chimeric-competent, embryo-derived stem cell lines unveil the plasticity of pluripotency in rabbits

ABSTRACT: Conventional rabbit embryonic stem cell (ESC) lines are derived from the inner cell mass (ICM) of pre-implantation embryos using methods and culture conditions established for primate ESCs (partial dissociation with collagenase and culture with FGF2). In the present work, we explored the capacity of rabbit ICM to give rise to ESC lines using conditions similar to those utilized to generate ESCs in mice.

ORGANISM(S): Oryctolagus cuniculus

PROVIDER: GSE79195 | GEO | 2017/02/12

SECONDARY ACCESSION(S): PRJNA315134

REPOSITORIES: GEO

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