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Genome-scale methylation assessment did not identify prognostic biomarkers in oral tongue carcinomas

ABSTRACT: DNA methylation profiling of heterogeneous head and neck squamous cell carcinoma (HNSCC) cohorts has been reported to predict patient outcome. We investigated if a prognostic DNA methylation profile could be found in tumour tissue from a single uniform subsite, the oral tongue. The methylation status of 83 comprehensively annotated oral tongue squamous cell carcinoma (OTSCC) formalin-fixed paraffin-embedded (FFPE) samples from a single institution were examined with the Illumina HumanMethylation450K (HM450K) array.

ORGANISM(S): Homo sapiens

PROVIDER: GSE79556 | GEO | 2016/07/18

SECONDARY ACCESSION(S): PRJNA316156

REPOSITORIES: GEO

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