Collagen XVII/Laminin-5 Activates Epithelia-to-Mesenchymal Transition and is Associated with Poor Prognosis in Lung Cancer
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ABSTRACT: We searched for candidate genes responsible for Epithelial-to-mesenchymal transition (EMT) by microarray analysis of cultured lung cancer cells with or without the property of spheroid formation. We found increased expression of a variety of adhesion molecules in cancer stem-like cells, including Collagen XVII. Further functional assays and signaling pathway were also investigated.
ORGANISM(S): Homo sapiens
PROVIDER: GSE80097 | GEO | 2016/12/07
SECONDARY ACCESSION(S): PRJNA317909
REPOSITORIES: GEO
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