Effects of exendin-4 in Brunner's glands of male GLP-1R-/- and wild-type control mice
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ABSTRACT: To gain insight into the biological functions of the highly expressed GLP-1R in Brunner’s glands, transcriptome analyses were conducted in male GLP-1R-/- and wild-type control mice. Analyses were performed 6 hours after a single s.c. dose of exendin-4 (1.0mg/kg s.c.), following 18 hours of two doses of exendin-4 (1.0 mg/kg s.c., administered at 0 and 9 hours), and in untreated controls. Brunner’s glands were isolated by laser capture micro dissection and extracted total RNA was used for microarray profiling.
ORGANISM(S): Mus musculus
PROVIDER: GSE80119 | GEO | 2016/07/01
SECONDARY ACCESSION(S): PRJNA317983
REPOSITORIES: GEO
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