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Prox1 (Prosper-related homeobox 1) transcription factor depletion effect on CGTH-W-1 cells.

ABSTRACT: Analysis of CGTH-W-1 follicular thyroid carcinoma cells transcriptome following 48 hrs siRNA-mediated depletion of PROX1. PROX1 is a homeobox transcription factor. PROX1 depletion decreases migratory ability, motility and invasivness and induces profound cytoskeleton changes of CGTH-W-1 cells. Results provide insight into the role of PROX1 in the thyroid cancer.

ORGANISM(S): Homo sapiens

PROVIDER: GSE80135 | GEO | 2016/07/31

SECONDARY ACCESSION(S): PRJNA318015

REPOSITORIES: GEO

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Prox1 (Prosper-related homeobox 1) transcription factor depletion effect on CGTH-W-1 cells.

Project description:Analysis of CGTH-W-1 follicular thyroid carcinoma cells transcriptome following 48 hrs siRNA-mediated depletion of PROX1. PROX1 is a homeobox transcription factor. PROX1 depletion decreases migratory ability, motility and invasivness and induces profound cytoskeleton changes of CGTH-W-1 cells. Results provide insight into the role of PROX1 in the thyroid cancer. Three biological replicates for a given condition

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