Transcriptomics

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Notch signaling promotes differentiation of mouse mucosal mast cells


ABSTRACT: Intestinal mucosal mast cells are critically involved in the development of food-induced allergic disorders. However, factors that induce differentiation of mucosal mast cells in the intestinal mucosa are largely unknown. To identify factors involved in mucosal mast cell differentiation, we compared the gene expression profiles between mucosal mast cells isolated from the small intestine and bone marrow-derived mast cells cultured in the presence of TGF-β or Notch ligand.

ORGANISM(S): Mus musculus

PROVIDER: GSE80139 | GEO | 2016/06/15

SECONDARY ACCESSION(S): PRJNA318022

REPOSITORIES: GEO

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