Transcriptomics

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Indole signaling and (micro)algal auxins decrease the virulence of Vibrio campbellii, a major pathogen of aquatic organisms


ABSTRACT: Vibrio campbellii BAA-1116 was used as a Harveyi clade model organism to determine the impact of indole signaling on virulence. Gene expression analysis of V. campbellii grown in LB35 broth with or without 100 μM indole revealed that indole decreased: (1) V. campbellii virulence in shrimp and prawn challenge assays, (2) exopolysaccharide production, and (3) swimming motility. The results also indicated that indole inhibits quorum sensing-regulated bioluminescence and blocks the three-channel quorum sensing system by interfering with quorum sensing signal transduction.

ORGANISM(S): Vibrio campbellii Vibrio campbellii CAIM 519 = NBRC 15631 = ATCC 25920

PROVIDER: GSE80484 | GEO | 2016/10/31

SECONDARY ACCESSION(S): PRJNA319043

REPOSITORIES: GEO

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