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The yellow fever virus capsid protein is a potent suppressor of RNA silencing that binds double stranded RNA.

ABSTRACT: In this study, we describe a viral suppressor of RNA silencing encoded by the prototype flavivirus, yellow fever virus (YFV). We show that the YFV capsid protein inhibits RNA silencing in the mosquito Aedes aegypti by interfering with Dicer. These results suggest a molecular arms race between vector and pathogen underlies the continued existence of flaviviruses in nature.

ORGANISM(S): Aedes aegypti

PROVIDER: GSE80691 | GEO | 2017/01/04

SECONDARY ACCESSION(S): PRJNA319716

REPOSITORIES: GEO

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