FOXO1 is an oncogenic mediator in AML1-ETO leukemia

ABSTRACT: Transcriptome analysis by RNAseq of human CD34+ hematopoietic stem and progenitor cells transduced with empty vector control(MIT), AML1-ETO (AE), wildtype FOXO1 (F WT) or FOXO1 DNA binding deficient mutant (F DB). We find wildtype FOXO1 partially recapitulates gene signature of AML1-ETO

ORGANISM(S): Homo sapiens

PROVIDER: GSE81084 | GEO | 2017/12/15

SECONDARY ACCESSION(S): PRJNA320467

REPOSITORIES: GEO