Transcriptomics

Dataset Information

0

Mutant p53 R270H induces invasion and metastasis of mouse intestinal tumor organoids through gain-of-function mechanism


ABSTRACT: Apc(D716) mutant mice develop benign intestinal adenoma, while Apc(D716) and p53 R270H compound mutant mice develop invasive adenocarcinoma in the intestine. We examined expression profile of tumor-derived organoids using Apc(D716), Apc(D716) p53 Null, Apc(D716) p53 R270H mutant mice by RNA sequencing, and identified mutant p53-induced gene set.

ORGANISM(S): Mus musculus

PROVIDER: GSE81441 | GEO | 2017/02/01

SECONDARY ACCESSION(S): PRJNA321536

REPOSITORIES: GEO

Dataset's files

Source:
Action DRS
Other
Items per page:
1 - 1 of 1

Similar Datasets

2022-03-02 | GSE130440 | GEO
2009-01-12 | E-GEOD-14336 | biostudies-arrayexpress
2009-01-12 | GSE14336 | GEO
2015-12-15 | E-GEOD-75989 | biostudies-arrayexpress
2024-01-23 | GSE238158 | GEO
2019-06-04 | GSE125260 | GEO
| PRJNA540264 | ENA
2015-12-15 | GSE75989 | GEO
2013-04-03 | E-GEOD-38983 | biostudies-arrayexpress
2017-02-09 | GSE54501 | GEO