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The Arabidopsis chromodomain-containing LHP1 colocalizes with histone H3 lysine27 trimethylation

ABSTRACT: The POLYCOMB proteins are required for maintenance of silent chromatin states mediated by H3K27 trimethylation in animals, but POLYCOMB homologues are not found in plant genomes. Using DamID-chip, we found that the Arabidopsis chromodomain-containing protein LHP1 localizes to chromatin associated with H3K27me3 genome-wide. Furthermore, the LHP1 chromodomain binds H3K27me3 with high affinity. These results suggest that LHP1 shares similar functions with POLYCOMB. Keywords: DamID-Chip

ORGANISM(S): Arabidopsis thaliana

PROVIDER: GSE8169 | GEO | 2007/09/07

SECONDARY ACCESSION(S): PRJNA101067

REPOSITORIES: GEO

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