Project description:Genome wide DNA methylation profiling of EGC with and without LVI. The Illumina Infinium 850k Human DNA methylation Beadchip was used to obtain DNA methylation profiles across approximately 820,000 CpGs in FFPE slides. Samples included 10 EGC patients with LVI and 10 negative controls.
Project description:Genome-wide methylation profiling of DNA extracted from the prefrontal cortex of post-mortem MSA patients (n=41) or normal, healthy controls (CTRLs; n=37). The Illumina Infinium MethylationEPIC BeadChip was used, investigating app. 850,000 CpG sites throughout the genome
Project description:Genome wide DNA methylation profiling of blood samples from patients with ASD and controls. The IlluminaInfinium HumanMethylation450 BeadChip was used to obtain DNA methylation profiles across approximately 450,000 CpGs. Samples included 53 individuals with idiopathic ASD (aged 2 to 14) and 10 age-matched controls.
Project description:Genome wide DNA methylation profiling of FASD patients versus healthy unexposed controls. The Illumina Infinium 450k Human DNA methylation Beadchip was used to obtain DNA methylation profiles across approximately 485,000 CpGs in peripheral blood samples. Samples included 28 healthy controls and7 FASD patients.
Project description:Genome wide DNA methylation profiling of rheumatoid arthritis (RA) patients and healthy controls. The Illumina Infinium 450k Human DNA methylation Beadchip was used to obtain DNA methylation profiles in peripheral blood mononuclear cells (PBMCs). Samples included 25 RA patients and 18 healthy controls.
Project description:Genome wide DNA methylation profiling of FASD patients versus healthy unexposed controls. The Illumina Infinium 450k Human DNA methylation Beadchip was used to obtain DNA methylation profiles across approximately 485,000 CpGs in peripheral blood samples. Samples included 64 healthy controls and 39 FASD patients.
Project description:Genome wide DNA methylation profiling of female Crohn's disease patients versus healthy female controls. The Illumina Infinium 450k Human DNA methylation Beadchip was used to obtain DNA methylation profiles across approximately 485,000 CpGs in peripheral blood samples. Samples included 25 healthy controls and 18 female patients with histologically confirmed CD.
Project description:Genome wide DNA methylation profiling of normal and ischemic stroke patients blood samples. The Illumina Infinium 850k Human DNA methylation Beadchip was used to obtain DNA methylation profiles across approximately 850,000 CpGs in liquid. Samples included 3 healthy people blood samples, 3 ischemic stroke patients blood samples.
Project description:This study performed a genome-wide methylation analysis of positively isolated CD19+ B cells in rheumatoid arthritis (RA) and healthy controls. The Ilumina HumanMethylation450 BeadChip was uset to obtain the methylation levels at >400,000 CpG sites. Samples include 49 RA patients and 73 healthy controls.
Project description:The study aimed to compare the DNA methylation differences between blood samples from sporadic breast cancer patients and healthy controls from a well-defined cohort in Uruguayan population. Infinium methylation arrays (450K Illumina) are used to identify genome-wide methylation differences between groups. The identified differently methylated CpG were further analyzed in an independent cohort of 80 breast cancer patients and 80 healthy controls.