Transcriptomics

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Gene expression profile of stage I lung adenocarcinoma and matched multi-site non-tumor lung samples


ABSTRACT: In this study, a unique geographical tissue sampling collection was obtained from patients that underwent curative lobectomy for stage I pulmonary adenocarcinoma. Tumor and non-tumor lung samples located at 0, 2, 4, and 6 cm away from the tumor were collected. Whole genome gene expression profiling was performed on all samples (n = 5 specimens x 12 patients = 60). Analyses were carried out to identify genes differentially expressed in tumor compared to adjacent non-tumor lung tissues at different distances from the tumor as well as to identify stable and transient genes in non-tumor tissues with respect to tumor proximity.

ORGANISM(S): Homo sapiens

PROVIDER: GSE83213 | GEO | 2017/05/23

SECONDARY ACCESSION(S): PRJNA325297

REPOSITORIES: GEO

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