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Gene expression profiling in the heart following exposure of rats to heat acclimation, its loss and re-induction.

ABSTRACT: To understand faster reinduction of heat acclimation, in this investigation we studied global stress associated genomic response during acclimation, following its loss and re-induction. Nylon cDNA Atlas Array was used. Collectively, the study comprised nine experimental groups of which six characterized experimental basal conditions: Controls-untreated, Short and Long term heat acclimated groups ( exposure to environmental heat at 34oC for 2 or 30 days respectively), Deacclimated group (24oC for 1mo) and Reacclimated groups (2d at 34oC following the deacclimation protocol). Three additional experimental groups: Controls, Short and Long term and Reacclimated rats (as above) were tested for genomic responses following subjection to heat stress at 41oC. Because of a dichotomy between genomic and physiological responses we hypothesize thst rapid reacclimation is linked to reprograming of gene expression. Keywords: heart, Left ventricle

ORGANISM(S): Rattus norvegicus

PROVIDER: GSE8329 | GEO | 2007/12/31

SECONDARY ACCESSION(S): PRJNA101321

REPOSITORIES: GEO

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Cardiac and Soleus muscles following exposure of rats to heat acclimation and exercise training

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2007-12-31 | GSE7799 | GEO

Cardiac and Soleus muscles following exposure of rats to heat acclimation and exercise training

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