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Gene expression from the New Zealand White rabbit calvarial defects treated with human particulated dentin

ABSTRACT: In this study, human particulated dentin (HPD) was developed. The characteristic of HPD was examinated by XRD, EDX and cytotoxicity test. HPD was used to implant in the calvarial defects of New Zealand White rabbits. bone tissue and blood samples were taken at 3, 5 and 7 days post-implantation for microarray experiment. The gene expression profiles and signaling pathways were monitored using GeneSpring software and Ingenuity Pathways Analysis (IPA), respectively. We used microarray and IPA to elucidate the global programme of gene expression and identified distinct classes of up- and down- regulated genes during HPD treated healing process.

ORGANISM(S): Oryctolagus cuniculus

PROVIDER: GSE83553 | GEO | 2016/06/21

SECONDARY ACCESSION(S): PRJNA326335

REPOSITORIES: GEO

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