Transcriptomics

Dataset Information

0

Exosomal microRNA, miR-1246, induces cell motility and invasion through the regulation of DENND2D in oral squamous cell carcinoma


ABSTRACT: To Identify of metastasis-related genes and metastasis-related miRNA in oral squamous cell carcinoma by miRNA profiling of HOC313-Parent, HOC313-LM and their respective exosomes carried out. As a result, miR-342-3p and -1246 were found candidate oncogenic miRNAs. To further identify the target genes of miR-1246 and miR-342-3p, we performed gene expression array analysis with HOC313-LM and HOC313-Parent (HOC313-P) transfected NT, miR-342-3p and miR-1246. Moreover, to identify tumor suppressor genes, gene expression profiles of each of transfected cells and HOC313-LM cells were analyzed by in silico analyses. As a result, DENND2D emerged as the possible target of miRN-1246.

ORGANISM(S): Homo sapiens

PROVIDER: GSE83981 | GEO | 2016/08/15

SECONDARY ACCESSION(S): PRJNA327741

REPOSITORIES: GEO

Dataset's files

Source:
Action DRS
Other
Items per page:
1 - 1 of 1

Similar Datasets

2016-08-15 | E-GEOD-83981 | biostudies-arrayexpress
2018-03-27 | GSE107870 | GEO
2016-04-29 | GSE71642 | GEO
2020-12-31 | GSE152950 | GEO
2016-04-08 | GSE80038 | GEO
2024-02-26 | GSE237144 | GEO
2024-02-26 | GSE220728 | GEO
2015-08-31 | E-GEOD-68373 | biostudies-arrayexpress
2014-07-31 | E-GEOD-45817 | biostudies-arrayexpress
2015-08-31 | GSE68373 | GEO