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ChIP-seq analysis of oligodendrocytes treated with demyelinating compound lysolecithin

ABSTRACT: We performed a series of ChIP-Seq analysis, and demonstrated that Olig2 and its downstream target Gpr17 were the key factors functioning in demyelination process. During demyelination, Olig2 was significantly up-regulated, and Gpr17 was the top ranking Olig2 transcriptional target.

ORGANISM(S): Rattus norvegicus

PROVIDER: GSE84011 | GEO | 2016/10/25

SECONDARY ACCESSION(S): PRJNA327818

REPOSITORIES: GEO

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