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ChIP-chip assay on circular chromosome conformation capture (4C) genomic DNA sample from human telomerase-immortalized corneal epithelial (HTCE) cells with the specification of CTCF binding


ABSTRACT: Ability of CTCF binding on various gene promoters is essential to regulate their expression. It's been demonstrated that cornea-specific Pax6 expression is regulated conversely by CTCF (Li et al.). circular chromosome conformation capture (4C) and ChIP-chip profiling have been performed using HTCE cells. This approach is to elicit the epigenetic mechanism involving CTCF-mediated chromatin remodeling that regulates Pax6 and some target gene interactions.

ORGANISM(S): Homo sapiens

PROVIDER: GSE84295 | GEO | 2017/02/09

SECONDARY ACCESSION(S): PRJNA328607

REPOSITORIES: GEO

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