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Comprehensive microRNA-sequencing of small extracellular vesicles derived from head and neck carcinoma cells reveals common secretion profiles

ABSTRACT: Exosomes are nano-sized (40-150 nm), membrane encapsulated vesicles that are released by cells into the extracellular space and function as intercellular signaling vectors through the horizontal transfer of biologic molecules, including microRNA (miRNA). Although secreted by both normal and malignant cells, there is evidence that cancer-derived exosomes enable the tumor to manipulate its microenvironment, contributing to the capacity of the tumor for immune evasion, growth, invasion, and metastatic spread.

ORGANISM(S): Homo sapiens

PROVIDER: GSE84306 | GEO | 2017/07/11

SECONDARY ACCESSION(S): PRJNA328779

REPOSITORIES: GEO

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Comprehensive microRNA-sequencing of small extracellular vesicles derived from HPV-positive head and neck carcinoma cells

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