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Mesenteric adipose tissue of rats treated with oleoyl-estrone

ABSTRACT: The aim of this work was to determine if OE treatment affects the expression of genes that regulate lipid metabolism in white adipose tissue. Gene expression in adipose tissue from female treated rats (48 hours) was analysed by hybridization to cDNA arrays and levels of specific mRNAs were determined by Real-Time PCR. Treatment with OE decreased the expression of 232 genes and up-regulated 75 other genes in mesenteric white adipose tissue. Short-term treatment with OE affects adipose tissue capacity to extract fatty acids from lipoproteins and to deal with fatty acid transport and metabolism. Keywords: Effects of a drug on gene expression

ORGANISM(S): Rattus norvegicus

PROVIDER: GSE8538 | GEO | 2007/07/25

SECONDARY ACCESSION(S): PRJNA101677

REPOSITORIES: GEO

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Mesenteric adipose tissue of rats treated with oleoyl-estrone

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