Transcriptomics

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Novel ABCG2 antagonists to reverse topotecan-mediated chemotherapeutic resistance in ovarian carcinoma xenografts.


ABSTRACT: In order to address the treatment difficulties associated with chemotherapetic resistance in ovarian cancer, we combined our compounds with topotecan and admininstered the mixture to chemoresistant Igrov1/T8 ovarian cancer cells in vitro and Igrov1/T8 xenografts in CB-17 SCID mice.

ORGANISM(S): Homo sapiens

PROVIDER: GSE85582 | GEO | 2017/02/10

SECONDARY ACCESSION(S): PRJNA338878

REPOSITORIES: GEO

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