Genomics

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MiRNA expression of lung cancer cells A549 and cisplatin (DDP) resistant lung cancer cells A549/DDP


ABSTRACT: To investigate the difference of miRNA expression between lung cancer cell A549 and its DDP-resistant cell strain A549/DDP, we have employed miRNA microarray expression to discover the difference expression of miRNAs of A549 cells and A549/DDP. We conducted RT-qPCR to examine the expression levels of top differential expressed miRNAs, namely, miR-197-5p, miR-4443, miR-642a-3p, miR-27b-3p and miR-100-5p, confirming low variability between two methods.

ORGANISM(S): Homo sapiens

PROVIDER: GSE85603 | GEO | 2016/08/16

SECONDARY ACCESSION(S): PRJNA338942

REPOSITORIES: GEO

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