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Gene expression in mouse 3T3-L1 adipocyte tissue culture treated with tunicamycin

ABSTRACT: Tunycamcin induces UPR/ISR and Inflammation in mouse 3T3-L1 adipocyte tissue culture. The early transcriptome changes were analyzed using high-density microarrays to better characterize the signaling pathways responding to tunicamycin, to be compared with similar experiments with CLA as the treatment. Their gene expression responses between 4 to 12 hr after treatment showed a common set of early gene expression changes indicative of a UPR/Inflammation stress response. Keywords: control/treatment time course

ORGANISM(S): Mus musculus

PROVIDER: GSE8682 | GEO | 2008/01/11

SECONDARY ACCESSION(S): PRJNA109035

REPOSITORIES: GEO

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Transcription profiling of mouse 3T3-L1 adipocyte tissue culture treated with tunicamycin

Project description:Tunycamcin induces UPR/ISR and Inflammation in mouse 3T3-L1 adipocyte tissue culture. The early transcriptome changes were analyzed using high-density microarrays to better characterize the signaling pathways responding to tunicamycin, to be compared with similar experiments with CLA as the treatment. Their gene expression responses between 4 to 12 hr after treatment showed a common set of early gene expression changes indicative of a UPR/Inflammation stress response. Experiment Overall Design: Mouse 3T3-L1 RNA for each time point was isolated from control and treatment samples for analysis on microarrays with two biological reps.

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2008-06-16 | E-GEOD-8681 | biostudies-arrayexpress

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Genome-wide microRNA expression profiling in tunicamycin treated NIH3T3 cells

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