Genomics

Dataset Information

0

Genome variation profiling of A204 parental and acquired-resistance cells treated with Pazopanib, Dasatinib and Sunitinib


ABSTRACT: Malignant rhadboid tumors (MRTs) are lethal paediatric cancers characterised by a deficiency in the SWI/SNF subunit SMARCB1. Here we employ an integrated molecular profiling and chemical biology approach to demonstrate that the receptor tyrosine kinases (RTKs) PDGFRα and FGFR1 are coactivated in MRT cells and that dual blockade of these receptors has synergistic efficacy. Genome variation profiling of A204 parental and acquired resistance cell line

ORGANISM(S): Homo sapiens

PROVIDER: GSE87208 | GEO | 2016/09/23

SECONDARY ACCESSION(S): PRJNA343883

REPOSITORIES: GEO

Dataset's files

Source:
Action DRS
Other
Items per page:
1 - 1 of 1

Similar Datasets

2016-09-08 | GSE78864 | GEO
2023-10-19 | GSE218385 | GEO
2023-10-20 | GSE218114 | GEO
2023-10-20 | GSE218111 | GEO
2023-10-20 | GSE218113 | GEO
2023-10-20 | GSE218112 | GEO
2023-10-20 | GSE218110 | GEO
| S-EPMC5673060 | biostudies-literature
| S-EPMC4555235 | biostudies-other
| S-EPMC3749583 | biostudies-literature