Folate deficiency enhances arsenic effects on ODC mouse skin gene expression
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ABSTRACT: We demonstrate that expression of key markers of keratinocyte differentiation is suppressed by exposure to sodium arsenite. Folate deficiency exacerbates this effect. In addition, cancer-related cell movement genes, and growth and proliferation genes are altered. Several redox-sensitive transcription factors are implicated in mediating these gene expression changes due to arsenic treatment and folate deficiency. Keywords: gene expression/microarray
ORGANISM(S): Mus musculus
PROVIDER: GSE8733 | GEO | 2007/08/10
SECONDARY ACCESSION(S): PRJNA101993
REPOSITORIES: GEO
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