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Ago2-RIP-chip in Dicer WT and KO macrophages

ABSTRACT: To determine the spectrum of miRNA targets regulated following Dicer deletion, we performed argonaute 2 (AGO2)-RNA Immunoprecipitation (RIP)-microarray in bone marrow-derived macrophages (BMDMs) from LysM-Cre/Dicerflox/flox/Apoe–/– and LysM-Cre/Dicerwt/wt/Apoe–/– mice. This analysis combined with miRNA profiling in Dicer wild type (WT) and knockout (KO) BMDMs may help to identify the miRNA targets regulated by Dicer deletion.

ORGANISM(S): Mus musculus

PROVIDER: GSE87717 | GEO | 2018/05/23

REPOSITORIES: GEO

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miRNA expression profiles in Dicer WT and KO bone marrow-derived macrophages

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