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Time series DNA methylation analysis of immature T-cells and reMAIT cells by using methylation array

ABSTRACT: To explore the molecular mechanisms underlying selective differentiation of MAIT-derived iPSCs into reMAITs, we conducted DNA methylation profiling based on a methylation array. We sampled reMAITs during the time course of differentiation from iPSCs as well as mature MAITs isolated from cord blood (CB MAITs). As control, we used immature T cells differentiated from hematopoietic stem cells (HSCs). For each of reMAITs and the immature T cells, we selected four time points: Start, Early, Middle, and Late.

ORGANISM(S): Homo sapiens

PROVIDER: GSE88937 | GEO | 2017/03/14

SECONDARY ACCESSION(S): PRJNA349150

REPOSITORIES: GEO

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