Transcriptomics

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Investigation of the physiological functions of PRDM6


ABSTRACT: PRDM6 belongs to the PRDM family of transcriptional repressors that all contain a PR domain and Zinc finger domains. Prdm6 has transcriptional repressor activity. Prdm6 may regulate factors that are involved in the differentiation / proliferation of smooth muscle cells, promoting proliferation. PRDM6 knockouts are embryonic lethal around 12.0 dpc knockout embryos eventually develop edema: cardiovascular defect vascularization defect in the yolk sac: dysorganized angiogenesis Keywords: cDNA array, yolk sac, murine embryo E10.5

ORGANISM(S): Mus musculus

PROVIDER: GSE9065 | GEO | 2008/04/01

SECONDARY ACCESSION(S): PRJNA102577

REPOSITORIES: GEO

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