Effect of dietary oils on hippocampus and liver gene expression
Ontology highlight
ABSTRACT:
GSM2558: Control
GSM2559: Control
GSM2560: Fungal oil (AA)
GSM2561: Fungal oil (AA)
GSM2562: Fish oil (DHA)
GSM2563: Fish oil (DHA)
GSM2564: Fish and Fungal oil (DHA + AA)
GSM2565: Control
GSM2566: Control
GSM2567: Control
GSM2568: Control
GSM2569: Fungal oil (AA)
GSM2570: Fungal oil (AA)
GSM2571: Fish oil (DHA)
GSM2572: Fish oil (DHA)
GSM2573: Fish + Fungal oil (DHA +AA)
GSM2574: Fish + Fungal oil (DHA +AA)
Keywords: ordered
ORGANISM(S): Mus musculus
PROVIDER: GSE91 | GEO | 2002/11/11
SECONDARY ACCESSION(S): PRJNA85477
REPOSITORIES: GEO
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Project description:Dietary effects of arachidonate-rich fungal oil and fish oil on murine hepatic and hippocampal gene expression.; Brain:; GSM2558: Control; GSM2559: Control ; GSM2560: Fungal oil (AA); GSM2561: Fungal oil (AA); GSM2562: Fish oil (DHA); GSM2563: Fish oil (DHA); GSM2564: Fish and Fungal oil (DHA + AA); Liver:; GSM2565: Control ; GSM2566: Control; GSM2567: Control; GSM2568: Control; GSM2569: Fungal oil (AA); GSM2570: Fungal oil (AA); GSM2571: Fish oil (DHA); GSM2572: Fish oil (DHA); GSM2573: Fish + Fungal oil (DHA +AA); GSM2574: Fish + Fungal oil (DHA +AA)
2007-12-13 | E-GEOD-91 | biostudies-arrayexpress
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Project description:Fish oil supplementation has been shown to alter gene expression of mononuclear cells both in vitro and in vivo. However, little is known about the total transcriptomic profile in healthy subjects after intake of fish oil compared to a control group. The objective was to examine the gene expression profile in peripheral blood mononuclear cells (PBMCs) in healthy subjects after intake of fish oil for seven weeks using whole-genome transcriptomic analysis. In a double-blinded randomized controlled study, healthy subjects received capsules containing either 8 g/d of fish oil (1.6 g/d EPA+DHA) (n=17) or 8 g/d of high oleic sunflower oil (n=19) for seven weeks. The results provide important information on how fish oil may modulate basic cellular processes involved in normal cell function and lymphocyte activation such as ER stress, cell cycle and apoptosis.
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2019-10-30 | E-MTAB-8306 | biostudies-arrayexpress
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