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ChIP-seq in neutrophils from Juvenile Idiopathic Arthritis

ABSTRACT: We used chromatin immunoprecipitation-sequencing to identify epigenetic marks associated with enhancer function (H3K4me1 and H3K27ac) from two children with untreated active JIA (ADU) and three children who were undergoing therapy with methotrexate but whose disease still remained active (ADT).

ORGANISM(S): Homo sapiens

PROVIDER: GSE92393 | GEO | 2019/09/28

REPOSITORIES: GEO

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RNA-seq in neutrophils from Juvenile Idiopathic Arthritis

Project description:In this study, we explored transcriptional complexity in human neutrophils from juvenile idiopathis arthritis and healthy control. We obtained differentially expressed genes among 3 ADU (active disease, untreated), 3 ADT (active disease, treated) and 2 HC (healthy control) samples using Cuffdiff2 software.

2017-06-13 | GSE92293 | GEO

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