Transcriptomics

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Simultaneous transcriptional and epigenomic profiling from specific cell types within heterogeneous tissues in vivo


ABSTRACT: This study introduces “NuTRAP”, a transgenic mouse that allows simultaneous isolation of cell type-specific translating mRNA and chromatin from complex tissues Using NuTRAP, we successfully characterize gene expression and epigenomic states of various adipocyte populations in vivo, To demonstrate general usefulness, we chateraterize histone states of in vivo hepatocytes.

ORGANISM(S): Mus musculus

PROVIDER: GSE92590 | GEO | 2017/01/24

SECONDARY ACCESSION(S): PRJNA358099

REPOSITORIES: GEO

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