Transcriptomics

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Precipitation of mRNAs by Ago2 and phosphorylation mutants


ABSTRACT: Argonaute (Ago) proteins associate with microRNAs (miRNAs), which guide them to complementary target mRNAs resulting in gene silencing. RNA coimmunoprecipitations (RIP) were performed with Ago2 and Ago2 mutants. The precipitated mRNAs were analyzed using one Affymetrix microarrays to compare the mRNA preciptation rates of mutants vs Ago2 wild type.

ORGANISM(S): Homo sapiens

PROVIDER: GSE92698 | GEO | 2017/06/22

SECONDARY ACCESSION(S): PRJNA358393

REPOSITORIES: GEO

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