Transcriptomics

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LPAR signaling activated in neural crest stem cells promotes melanoma cell growth, invasion and therapy resistance [HumanWG6_V2]


ABSTRACT: To pinpoint developmental pathways that are up-regulated both in neural crest stem cells (NCSC) and in melanoma cells but not in melanocytes, we carried out computational analyses to compare gene expression profiles of human skin-derived NCSC, epidermal melanocytes and melanoma cells. Our aim was to preselect genes that exhibit high mRNA expression levels both in melanoma cells and in NCSC but low levels in melanocytes.

ORGANISM(S): Homo sapiens

PROVIDER: GSE92763 | GEO | 2017/12/01

SECONDARY ACCESSION(S): PRJNA358578

REPOSITORIES: GEO

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