Transcriptomic analysis of strains evolved for anaerobic xylose utilization [Y223_Y127_Y128]
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ABSTRACT: Engineering microbes with novel metabolic properties is a critical step for production of biofuels and biochemicals. Synthetic biology enables identification and engineering of metabolic pathways into microbes; however, knowledge of how to reroute cellular regulatory signals and metabolic flux remains lacking. Here we used network analysis of multi-omic data to dissect the mechanism of anaerobic xylose fermentation, a trait important for biochemical production from plant lignocellulose. We compared transcriptomic, proteomic, and phosphoproteomic differences across a series of strains evolved to ferment xylose under various conditions.
ORGANISM(S): Saccharomyces cerevisiae
PROVIDER: GSE92907 | GEO | 2019/03/12
REPOSITORIES: GEO
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